The NIOH / NHLS, hold the blueprint for ASPIRE (Aerogen Science – Promoting Innovative Research) laboratory, which is a state-of-the-art facility and the ONLY ONE OF ITS KIND IN THE WORLD. It serves as a global resource for research into preventive interventions that reduce airborne infectious pathogens like Mycobacterium tuberculosis, the causative agent of tuberculosis (TB).
The ASPIRE lab is a custom-made high containment biosafety level 3 laboratory, which is different from other BSL 3 laboratories. The lab aims to prevent bioaerosol transmission by assessing the efficacy of infection control devices and the performance of new innovation or products. This is to ensure they meet disinfection standards and concur with stated claims.
Click on the video below to learn more about the Services the ASPIRE Lab provides.
This Unit is able of screening compounds, such as chemicals, particulates and nanomaterial, using validated in vitro genotoxicity and cytotoxicity test systems, all performed under Good Laboratory Practice (GLP) guidelines.
Genotoxic tests are designed to experimentally determine the ability a compounds to adversely affect the genetic material (DNA), in so doing damaging the genetic material either directly or indirectly in cells.
The Genotoxicity assays include:
- Comet Assay or Single cell gel electrophoresis
- In vitro Micronucleus Assay
For more Information about the Genotoxicity Unit, contact: