Authors: De Jager P, Churchyard CJ, Ismail N, Kyaw KKK, Murray J, Nshuti L, Rees D, Reid A.

Source: Occup Health S Afr 2014; 20(1):6-11


Abstract: Clinical guidance on the treatment of latent tuberculosis in people with silicosis is provided. This guideline, developed during a workshop held in July 2013, is particularly applicable to resource-constrained, tuberculosis endemic settings and has been aligned with World Health Organization and South African National Department of Health guidelines for the treatment of latent tuberculosis infection. Major changes from the previous guideline include 1) utilization of tuberculin skin testing to guide treatment of latent tuberculosis, and 2) the increase of the duration of isoniazid treatment to 36 months.

Keywords: Isoniazid, Latent Tuberculosis, silicosis, lower-middle Income Countries, Mining